In vitro fertilization (IVF) is a complex series of procedures used to help with fertility or prevent genetic problems and assist with the conception of a child. In IVF procedure woman's eggs are removed from her ovaries and fertilized with the man's sperm in a laboratory.
Starting the IVF treatment process can be an exciting and nerve-wracking experience. Usually, IVF is pursued only after all other fertility treatments have failed.
In India, IVF cost is very low rather than in other western countries. India is the most popular place for IVF treatment due to its low cost.
Usually, IVF treatment cost depends on the number of IVF cycle a patient takes up. If a woman can conceive in 2 IVF- cycles then the IVF treatment cost will be lesser than the one who undergoes 5 cycles of IVF to conceive. The cost of IVF treatment in India also depends upon the women's age, fertility issues, medical history.
Please fill the form for the exact costing of IVF Treatment in your case.
Finally...My wife got conceived with 4 months of treatment in this Centre. Before coming to this hospital, we had visited many hospitals. Finally, we got the best and best treatment here and succeeded with the 2nd cycle of IVF. The way the Doctor treated her patients is excellent. And the hospital staff too are very co-operative. Thanks, Doctor for helping us to be parents...We need the same type of caring till the birth of the child. We will never forget your help in our life.
I'd like to thank the staff at IVF Center for being so kind and patient with me and my partner throughout the entire treatment process. The doctors were very nice and were willing to address all my concerns and worries. They made me feel like a valued patient and treated me with the utmost respect. They used the latest technology as the whole process from diagnoses to surgery seamlessly and comfortably. I felt just at home. 10/10 would recommend.
All the way came from London to this hospital not on recommendation but I will recommend this hospital. found this hospital through their reviews Excellent experience from the beginning...all the consultants n staffs are extremely kind and helpful n easy to communicate all problems and immediate resolution to all worries. I strongly recommend everyone to come here, if u have any kind of issue. Don't take too much time to go for IVF. It's good to meet ur IVF Dr. On time.
This is an amazing place with so much positivity. After having two failed IVF I was very much confused about my next IVF. Then the doctor made me understand the reasons and possible treatment available for my failures. Her honest advice and expertise helped me to conceive and now I am blessed with a baby boy. Everyone at this center is very supportive. Especially the doctor who handled my case so nicely. She guided me throughout my pregnancy as well. I would recommend all those couples who have difficulty in getting pregnant to consult this Center .
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Initiating an IVF treatment process can be a stimulating and nerve-wracking experience. IVF is usually pursued only after other fertility treatments have failed. You may have been trying to get pregnant for months, or perhaps years or years.
However, this is not always the case . Sometimes IVF is the first treatment attempted .
For example, the following cases, IVF there is a possibility that becomes the first option .
Nevertheless, even in these cases, IVF attempts to become pregnant over the years, some carried out the fertility test may come in after you . 1
Just looking at the ultrasound, blood test, and injection schedules can make you feel fragile. (And that's before the drug ruins your mood!) Plus, there's an IVF cost , especially if you're paying for it , and even if you feel worried Not surprising.
However, the more you understand what will happen next, the more you will have control. All clinic protocols are slightly different and treatment is tailored to the individual needs of the couple, but here is a step-by-step breakdown of what is commonly done during IVF, as well as risks, costs, and Provides information about the following: If the IVF treatment cycle fails .
Emily over- Roberts, illustrations by berry-well door
Based on in vitro fertilization this
IVF stands for in vitro fertilization. In vitro means "in the laboratory" and fertilization means conception. In IVF , many eggs are usually collected (collected with a transvaginal ultrasound-guided needle) and placed in a Petri dish containing specially washed sperm cells (collected by masturbation).
If all goes well, some of the recovered eggs will be fertilized by sperm cells into embryos. Of those of healthy embryos 1 or 2 one but it will be moved to your uterus.
In some cases, sperm cells require special help during the fertilization process. ICSI or egg intracytoplasmic sperm injection method can be used. This is assisted reproductive technology that involves injecting a single sperm cell into an egg.
This is a severe male infertility, eggs that have been frozen previously saved, pre-implantation embryos of genetic testing ( PGT case of), or past IVF cycle can be carried out in case of failure in the fertilization stage. 2
However, the ovaries need to be stimulated before the eggs can be collected. Without the help of fertility drugs, your body usually, every month 1 one (or 2 only mature eggs of the pieces). Traditional in vitro fertilization requires a lot of eggs. Injectable ovulation-inducing agent, to stimulate the ovaries, for the recovery 1 will be used in order to mature the more than a dozen of eggs. 3
However, this is not always the case. Minimal irritation IVF (also known as mini IVF ) , oral fertility drugs or very low dose injections can be used to stimulate just a few eggs.
IVF success rate
IVF is quite successful. About 156 , 000 According to the survey of women , the average birth rate of the first cycle 29.5 was%. 4 This , the success rate of the natural cycle of the couple with a healthy reproductive capacity comparable to
Your highest probability of success may come from repeated treatment cycles. In this same study, 6 times of IVF after the cycle, the cumulative birth rate is 65.3 was found to be%. These six cycles usually lasted for two years .
Age plays an important role in your success, as is the reason for your infertility. Egg donors the use also have an impact on your success possible.
Always discuss your personal chances of success with your doctor before starting treatment. Your doctor can't tell you for sure if the treatment works for you, but she should have an idea of your odds in relation to the average and other patients like you .
IVF costs and Squirrel click
IVF is expensive. In addition, insurance is often not covered, making treatment out of reach for many in need. In 5 , in fact , the couple imagining in four who need IVF found to be only research, can actually get the treatment they need.
Often cited IVF of the average cost is 1 per cycle 12 , 000 from $ 15,000 is between $ . Some say that this estimate is actually below reality and that the average out-of-pocket cost is high.
According to one study, the average couple first IVF cycle 19 234 dollar payment , for each additional cycle 695.5 was paid an additional dollar. (Why that such a difference is to you? Partially between the first and then, these 2 -th and 3 part of the second cycle for a frozen embryo transfer is.)
This is all for traditional plain IVF . Costs are high if additional techniques such as ICSI , PGT , assisted hatching , egg donors, and pregnant carriers are required. Sometimes much higher.
There are several ways to reduce the cost of IVF treatment and get financial support. All options should be considered before deciding if you can afford treatment.
Of in vitro fertilization safety and squirrel -click
IVF is generally safe, but like any other medical procedure, it is at risk. Before you start, your doctor should explain all possible side effects and risks of each procedure .
Ovarian hyperstimulation syndrome ( OHSS ) occurs in 10 % of women receiving IVF treatment . For most women, the symptoms are mild and easy to recover. A small percentage for 7 , OHSS can be more serious and may require hospitalization. Less than 1 % of women collecting eggs experience thrombosis or renal failure due to OHSS .
Egg collection can cause cramps and discomfort during or after the procedure. Rare complications include accidental puncture of the bladder, intestines, or blood vessels. Pelvic infection ; or bleeding from blood vessels in the ovaries or pelvis. 8
If an intrapelvic infection occurs, it is treated with intravenous antibiotics. In rare cases of severe infection, the uterus, ovaries, and fallopian tubes need to be surgically removed .
Embryo transfer can cause mild seizures during the procedure. Rarely, women also experience seizures, bleeding, or spots after transfer. In very rare cases, infections can occur. Infections are usually treated with antibiotics .
There are multiple risks, including twins, triplets, or more. Multiple pregnancies can be dangerous for both the baby and the mother. It is important to discuss the number of embryos to be transplanted with your doctor, as transplanting more than necessary increases the risk of twins and above . Embryo PGT If you have been tested with, usually 1 will be only one of embryo transplant.
Some studies have found that IVF may increase the risk of some very rare birth defects, but the risk is still relatively low. According to 9 studies, the use of ICSI in in vitro fertilization may increase the risk of infertility and sexual birth defects in male children in certain cases of male infertility . However, this risk is very low ( less than 1 %). Ten
Pre-treatment of the cycle Le
Oral contraceptives may be taken in the cycle before IVF treatment is scheduled. This may look backward — are you trying to get pregnant?
The use of oral contraceptives before the treatment cycle has been shown to increase the chances of success. It may also reduce the risk of ovarian hyperstimulation syndrome and ovarian cysts. 11
However, not all doctors have used oral contraceptives in previous cycles. Another possibility is that your doctor asks you to track the ovulation of the previous cycle. In most cases, she is of ovulation prediction kit is recommended to use it. However, we may also suggest a graph of basal body temperature, especially if you have experience in graphing cycles.
Second, you should inform your doctor as soon as you detect ovulation. Someday, after ovulation, in the infertility clinic, you have to start shooting of GnRH or of GnRH . These are injections, but some are available as nasal drops or implants.
These drugs give the doctor complete control over ovulation once the treatment cycle begins. If you don't get your cycle yourself, your doctor may take yet another approach. In this case, he may prescribe progesterone in the form of . This will bring your period.
In this case, your doctor will probably ask you to start taking a GnRH agonist or antagonist about 6 days or more after the first pill . Again, this can be different. Always follow your doctor's instructions.
Menstruation came et al.
The first official day of the treatment cycle is the day when your period begins. (Step 1 in the previous might feel like the start of the medicine that started already.)
On the second day of menstruation, your doctor may order a blood test and an ultrasound. This will be a transvaginal ultrasonography. Ultrasonography during menstruation is not always comfortable, but keep in mind that it is the same for all women who undergo IVF.
These first day ultrasounds and blood tests are called baseline blood tests and baseline ultrasounds. In your blood test, your doctor will check your estrogen levels, especially your E2 or. This is to make sure that the ovaries are "sleeping." This is the intended effect of or a GnRH antagonist .
Ultrasound is to check the size of your ovaries. Your doctor will also look for ovarian cysts. If you have cysts, your doctor will decide how to deal with them. Sometimes your doctor will delay treatment for just a week. Most cysts resolve spontaneously over time. In other cases, your doctor may use a needle to aspirate the cyst (suck the fluid) .
These tests are usually fine . If everything looks normal, treatment is continued .
Ovarian stimulation and monitoring grayed
The next step is ovarian stimulation with fertility drugs. Depending on your treatment protocol, this may mean somewhere in 1 to 4 shots daily for about 1 week to 10 days.
You are probably now a self-injection pro, as and other GnRH agonists can also be injected. Your clinic should teach you how to inject yourself before treatment begins. Some clinics offer classes with tips and instructions.
Learn more about fertility drugs that you may take during in vitro fertilization.
During ovarian stimulation, your doctor will monitor follicle growth and development.
Initially, this may include blood and ultrasonography every few days. Your doctor will monitor your levels. During ultrasonography, the doctor monitors the growth of oocytes . (The oocyte is the egg of your ovary.)
Monitoring the cycle is very important . This is how your doctor decides how to adjust your medication .
You may need to increase or decrease the dose . The size of the largest follicle is 16 ～18 Mm Once you become, the clinic will want to meet you probably every day .
Formation of final oocyte Mature
The next step in IVF treatment is to trigger the oocyte to go through the final stages of maturation. Eggs must complete their growth and development before they can be collected .
This final growth is triggered by human (hCG ). This brand name includes. The timing of this shot is very important. If given too early, the eggs will not mature sufficiently. If given too late, the eggs may be "too old" and will not fertilize properly. 13
The daily ultrasound at the end of the last step is to properly time this trigger shot. Normally, HCG injections, 4 or more follicles 18 ～20 Mm to grow to the size of the level is 2 , 000 Pg / ML is done when exceeded.
This shot is usually a single injection. Your doctor will probably give you the exact time to make this shot . Be sure to follow these instructions!
IVM vs IVF
In traditional in vitro fertilization, the egg must complete its development and growth before it can be recovered. The treatment of IVM is a little different. IVM stands for in vitro maturity . This is a relatively new technology, similar to IVF , but very different at this point in the process.
During IVM , eggs are collected before going through all stages of maturation. No "trigger shot" occurs during IVM . The recovered eggs mature in a laboratory environment. Once the egg has matured, the remaining steps follow the IVF process.
What if the follicle does not grow?
Up to this point, we assume that the ovarian stimulant is functioning properly. But that doesn't always work. Sometimes the follicle does not grow. Your doctor might increase the medicine, but if your ovary does not respond still, cycle probably be canceled will be.
This does not mean that another cycle will not work. You may just need a different drug. However, if this occurs repeatedly, doctors egg donor or embryo the use proposed to you there is a case. At this point it is advisable to get a second opinion before proceeding.
What if I 'm at risk for OHSS?
Another 1 one of the possible problems is that the reaction of the ovary is too good. Severe ovarian hyperstimulation syndrome ( OHSS ) If the doctor has determined that there is a risk of developing, the trigger shot is canceled, and the cycle will stop at this point.
Another possibility is that your doctor will collect and fertilize the eggs, but delay embryo transfer. This is because pregnancy may worsen and prolong recovery from OHSS . Once your body recovers, you can try frozen embryo transfer.
In the next cycle, your doctor may suggest a lower dose of the drug, try another drug before the cycle begins, or suggest IVM instead of IVF (as explained above) .
What if I ovulate prematurely ?
Although uncommon, the cycle may be canceled if ovulation occurs before recovery occurs. Once the egg ovulates naturally, it cannot be recovered. Your doctor will probably tell you to refrain from sexual intercourse .
It is important to follow these instructions! You may have ovulated up to 12 eggs. Maybe more. If even half of those eggs become pregnant naturally, both mothers and children are at risk.
How often are IVF cycles canceled?
Cancellation occurs in 10 % to 20 % of the IVF treatment cycle . 18 The likelihood of cancellation increases with age, and people over the age of 35 are more likely to experience treatment cancellation.
Approximately 34 to 36 hours after receiving the hCG shot , eggs will be collected. 19 It is normal to be nervous about surgery, but most women do it without much problem or pain.
Before recovery, the anesthesiologist administers the drug intravenously to relax and eliminate pain. Light sedatives are usually used, which allow you to "sleep" throughout the procedure. This is not the same as general anesthesia used during surgery. Side effects and complications are less common.
When the drug works, doctors use transvaginal ultrasound to guide the needle from the back wall of the vagina to the ovaries. Then use the needle to aspirate the follicle or gently aspirate the liquid and oocytes from the follicle into the needle. For each follicle 1 there is one of the oocyte. These oocytes are transferred to the embryology laboratory for fertilization .
The number of oocytes recovered varies, but can usually be estimated prior to ultrasound recovery. The average number of oocytes 8 ~ 15 , the 95 patients over% at least 1 has recovered one oocyte. twenty one
After the search procedure, it will be held for several hours to make sure everything is normal. Light spots are common, as well as some lower abdominal cramps, almost felt, after a better day or so. In addition, 10 % of patients are instructed to be aware of the signs of ovarian hyperstimulation syndrome, which is a side effect of using fertility drugs during IVF treatment . 19
Ova received fine
While recovering from recovery at home, the aspirated follicles are searched for oocytes or eggs. Not all follicles contain oocytes .
Once the oocyte is found, it is evaluated by an embryologist. If the egg is too mature, fertilization may not be successful. If they are not mature enough, the developmental laboratory may be able to stimulate them until they are mature in the laboratory .
Fertilization of oocytes should occur in 12 to 24 hours. twenty two
Your partner will provide a semen sample the same morning you collect. The stress of the day can be difficult for some, so your partner may provide a backup semen sample early in the cycle, just in case.
When the semen sample is ready, it undergoes a special washing process to separate the sperm from the others contained in the semen. Embryologist chooses the "good-looking sperm", about to each culture dish containing the oocytes 10 , 000 and put the pieces of the sperm . Culture dishes are stored in a special incubator and tested for signs of fertilization after 12 to 24 hours .
Except for severe male infertility, 70 % of oocytes fertilize. 23 In the case of severe male infertility in, ICSI (pronounced ICK -See if put to simply culture dish instead of), can be used to fertilize the eggs. With ICSI , embryologists select sperm that look healthy and use special fine needles to inseminate the oocytes.
After about recovery 3 ～5 in the day, embryologist will identify the embryos that appear to most health. This is usually done visually (using a microscope), but in some cases genetic screening is done. This is known as Preimplantation Genetic Diagnosis ( PGD ) or Preimplantation Genetic Diagnosis ( PGS ) 24 .
Occasionally, in PGD / PGS , embryos are cryopreserved and transplantation is delayed until the next cycle . Otherwise, a "new" transfer will occur. The procedure for embryo transfer is the same as for IUI treatment . No anesthesia required.
During embryo transfer, a thin tube or catheter passes through the cervix. You may experience very mild cramps, but nothing more. The embryo is transplanted through a catheter with a small amount of fluid. twenty five
The number of embryos to be transplanted depends on the quality of the embryos and discussions with your doctor. Depending on age, 1 to 5 embryos may be transplanted. 2 is possible to transplant a single embryo is the most common options .
More many physicians, 1 implanted with only one embryo, it is proposing to freeze the rest. This is known as Selective Single Embryo Transfer ( eSET ) and can reduce the risk of multiple pregnancies. Pregnancy of only one healthy baby reduces the risk of pregnancy complications. 26 Talk to your doctor to find out if selective single embryo transfer is best for you.
After the transfer, I lie down for a few hours (bring a book) and go home. If "extra" high quality embryos remain, you may be able to freeze them. This is called embryo cryopreservation. If this cycle is unsuccessful in frozen embryo transfer , they can be used later, or they can be donated.
Progesterone support and 2 -week wait machine
After the day of recovery, start giving yourself a progesterone supplement before embryo transfer. Progesterone during IVF treatment is usually given as an intramuscular self-injection as progesterone in oil. (More shots!) However, progesterone supplements may be taken as pills, vaginal gels, or vaginal suppositories .
With the exception of progesterone, the next two weeks haven't really happened much. In a sense, two weeks after transfer can be emotionally more difficult than two weeks of treatment. During the previous step, you probably visited your doctor every other day. Well, after the transfer, the activity suddenly settles down .
You may have many questions about waiting for two weeks. Can you have sex? What if I have cramps? Of course, your doctor is the number one source of concern for you .
What can you , 2 weeks waiting , only to check whether the pregnancy occurs. During this waiting time, it helps you stay busy in your life and avoid sitting down and thinking about the success of your treatment.
Pregnancy tests and follow-up flop
About embryo transfer 9 ～12 in the days after the pregnancy test you ordered it is. 27 This is usually a serum pregnancy test (more blood tests) and also includes a progesterone level test. The test may be repeated every few days.
The test is positive case is, you may need to continue to further take a few weeks progesterone supplements. Doctors also occasionally perform blood and ultrasonography to monitor pregnancy and to monitor miscarriage and ectopic pregnancy.
Possible pregnancy risk of in vitro fertilization of
Doctors also monitor whether treatment has led to multiple pregnancies. IVF is at high risk for multiple pregnancies, which poses a risk to both mothers and babies. 28 of the risk of multiple pregnancy , including premature labor and delivery, maternal hemorrhage, C- section delivery, high blood pressure is pregnancy-induced, and gestational diabetes .
If it is a higher pregnancy ( 4 or more), doctors may discuss reduction options in a procedure called the fetal " reducing multifetal pregnancies." This is to increase the chances of a healthy and successful pregnancy. It may be done.
Women who are pregnant with IVF are more likely to experience spotting early in pregnancy but are more likely to resolve spotting without harming their pregnancy. 30
The risk of miscarriage is about the same for women who become pregnant naturally and increases with age. Miscarriage rates for young women in their 20s are as low as 15 %, and miscarriage rates for women over the age of 40 can exceed 50 %. 31
What is the concept of ectopic pregnancy and IVF at risk of 2 % to 4 %? If 32 , you develop OHSS from fertility drugs and you become pregnant, recovery may take some time.
IVF and treatment has failed come
If the pregnancy test is negative 12 to 14 days after transfer , your doctor will ask you to stop taking progesterone. Then wait for your period to begin .
The next steps will be decided by you, your partner, and your doctor. If this is the first cycle, another cycle may be recommended. Remember that the best chance of success is after running a few cycles .
Failure of a treatment cycle has never been easier. It's a pain. However, 1 even if one of the cycle fails, please note that does not mean that even if the retry does not succeed. After the treatment cycle has failed you can take many steps there is a will .